腸道微生物和腦神經系統的關聯
腸道微生物和腦神經系統之間存在著『腸-腦軸線』,通過神經、內分泌和免疫途徑等進行溝通。此外,研究還表明,腸道微生物還能夠影響大腦神經傳遞物質的產生,例如血清素、多巴胺和γ-氨基丁酸(GABA)等(註1,2,3),進而影響我們的:情緒、行為、認知和消化系統等。
所以,要如何讓心情開心?最簡易的方式就是『腸道開心、心情就跟著開心』
註:
Bravo, J. A., Forsythe, P., Chew, M. V., Escaravage, E., Savignac, H. M., Dinan, T. G., ... & Cryan, J. F. (2011). Ingestion of Lactobacillus strain regulates emotional behavior and central GABA receptor expression in a mouse via the vagus nerve. Proceedings of the National Academy of Sciences, 108(38), 16050-16055.
Hsiao, E. Y., McBride, S. W., Hsien, S., Sharon, G., Hyde, E. R., McCue, T., ... & Mazmanian, S. K. (2013). Microbiota modulate behavioral and physiological abnormalities associated with neurodevelopmental disorders. Cell, 155(7), 1451-1463.
Yano, J. M., Yu, K., Donaldson, G. P., Shastri, G. G., Ann, P., Ma, L., ... & Hsiao, E. Y. (2015). Indigenous bacteria from the gut microbiota regulate host serotonin biosynthesis. Cell, 161(2), 264-276.